Exercise Capacity and Fatigue in Post-COVID-19 Patients

Authors

  • Hadeel Alqahtani Physical Therapy Department, King Fahd Medical City, Riyadh Second Health Cluster, Riyadh, Saudi Arabia.
  • Tamadher Aljouiee Physical Therapy Department, King Fahd Medical City, Riyadh Second Health Cluster, Riyadh, Saudi Arabia.
  • Mohammed Alsultan Physical Therapy Department, King Fahd Medical City, Riyadh Second Health Cluster, Riyadh, Saudi Arabia.
  • Mohsen Ayyash School of Mathematical Sciences, Universiti Sains Malaysia, USM Penang 11800, Malaysia.
  • Amani Abu-shaheen Research Center, King Fahd Medical City, Riyadh Health Cluster, Riyadh, Saudi Arabia.

DOI:

https://doi.org/10.52609/jmlph.v4i3.125

Keywords:

COVID-19, Endurance, Exercise Capacity, Fatigue

Abstract

Background:

While many researchers have investigated the influence of COVID-19 on fatigue and quality of life, its impact on exercise capacity has been little considered. It is therefore our aim to examine the impact of COVID-19 on exercise capacity and fatigue among individuals who have recovered from the virus.

Methods:

A cross-sectional study was conducted at the outpatient physical therapy department of a tertiary hospital and Primary health care center. The study comprised 116 participants divided into two groups: a normative group composed of individuals who had not been infected with COVID-19 in the past three months, and a control group consisting of those who had contracted COVID-19 within the preceding three months. The one-minute sit-to-stand test (1STST) was carried out to assess exercise capacity, following which fatigue was measured using the validated Arabic version of the Fatigue Severity Scale (FSS).

Results:

Of the 116 participants enrolled in this study, 76 (65.5%) were in the normative group and 40 (34.5%) in the control group. Following the intervention, the mean FSS score differed significantly between the normative (26.6; SD 10.9) and the control group (36.9; SD 14.8); p-value < 0.001, with participants in the control group reporting higher levels of weariness than those in the normative group. Moreover, as measured by 1STST, the median number of sit-to-stand repetitions completed by participants in the normative group (21.0) was considerably greater than that of the control group (20.0); p-value = 0.025.

Conclusion:

Participants in the control group reported higher levels of fatigue and demonstrated lower exercise capacity than those in the normative group.

References

- Pescaru CC, Marițescu A, Costin EO, Trăilă D, Marc MS, Trușculescu AA, Pescaru A, Oancea CI. The Effects of COVID-19 on Skeletal Muscles, Muscle Fatigue and Rehabilitation Programs Outcomes. Medicina (Kaunas). 2022 Sep 1;58(9):1199. doi: 10.3390/medicina58091199. PMID: 36143878; PMCID: PMC9500689.

- Zhang JJ, Dong X, Liu GH, Gao YD. Risk and Protective Factors for COVID-19 Morbidity, Severity, and Mortality. Clin Rev Allergy Immunol. 2023 Feb;64(1):90-107. doi: 10.1007/s12016-022-08921-5. Epub 2022 Jan 19. PMID: 35044620; PMCID: PMC8767775.

- Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review. J. Am. Med. Assoc. 2020;324(8):782–793.

- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. 10223.

- Zhang Y, Ma ZF. Impact of the COVID-19 pandemic on mental health and quality of life among local residents in Liaoning Province, China: a cross-sectional study. Int. J. Environ. Res. Publ. Health. 2020;17(7):2381

- Baig AM. Chronic COVID syndrome: need for an appropriate medical terminology for long-COVID and COVID long-haulers. J Med Virol 2020; 93:2555–6

- Liu B, Jayasundara D, Pye V, Dobbins T, Dore GJ, Matthews G, Kaldor J, Spokes P. Whole of population-based cohort study of recovery time from COVID-19 in New South Wales Australia. Lancet Reg Health West Pac. 2021 Jul;12:100193. doi: 10.1016/j.lanwpc.2021.100193. Epub 2021 Jun 25. PMID: 34189493; PMCID: PMC8225991.

- Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Archives of Neurology. 1989; 46(10): 1121-1123

- Al-Sobayel HI, Al-Hugail HA, AlSaif RM, Albawardi NM, Alnahdi AH, Daif AM, Al-Arfaj HF. Validation of an Arabic version of fatigue severity scale. Saudi Medical Journal. 2016; 37(1): 73.

- IBM Corp. Released 2019. IBM SPSS Statistics for windows, Version 26.0. Armonk, NY: IBM Corp

- Joshi R, Khandare S, Rasane M, Banerjee R, Harilal S, Salvi R. Impact of COVID-19 on RPE & Functional Status of Patients Using PCFS Scale: A Cross-Sectional Survey. International Journal of Current Research and Review. 2022 Jan; 14(2): 17-22.

- Kutukcu EC, Capanoglu MS, Uyaroglu OA, Yagli NV, Saglam M, Ince DI, Ozisik L, Basaran NC, Guven GS. Factors Associated with Exercise Capacity and Functional Balance in Post-COVID-19 Syndrome. European Respiratory Journal. 2023; 62: PA4535

- Kaulback K, Schwellnus M, Sewry N, Jordaan E, Wood P. Rating of Perceived Exertion Associated With Acute Symptoms in Athletes With Recent SARS-CoV-2 Infection: Athletes With Acute Respiratory InfEction (AWARE) VI Study. Journal of Athletic Training. 2024 Jan 1;59(1):90-8.

- Halpin SJ, McIvor C, Whyatt G, Adams A, Harvey O, McLean L, Walshaw C, Kemp S, Corrado J, Singh R, Collins T. Postdischarge symptoms and rehabilitation needs in survivors of COVID‐19 infection: A cross‐sectional evaluation. Journal of Medical Virology. 2021 Feb;93(2):1013-22.

- Stavem K, Ghanima W, Olsen MK, Gilboe HM, Einvik G. Prevalence and determinants of fatigue after COVID-19 in non-hospitalized subjects: a population-based study. International Journal of Environmental Research and Public Health. 2021 Feb;18(4):2030.

- Petersen MS, Kristiansen MF, Hanusson KD, Danielsen ME, á Steig B, Gaini S, Strøm M, Weihe P. Long COVID in the Faroe Islands: a longitudinal study among nonhospitalized patients. Clinical Infectious Diseases. 2021 Dec 1;73(11):e4058-63.

- Goërtz YM, Van Herck M, Delbressine JM, Vaes AW, Meys R, Machado FV, Houben-Wilke S, Burtin C, Posthuma R, Franssen FM, Van Loon N. Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? ERJ Open Research. 2020 Oct 1;6(4).

- Ekstrand E, Brogårdh C, Axen I, Fänge AM, Stigmar K, Hansson EE. Perceived consequences of post-COVID-19 and factors associated with low life satisfaction. International Journal of Environmental Research and Public Health. 2022 Nov 19;19(22):15309.

- Hasenoehrl T, Palma S, Huber DF, Kastl S, Steiner M, Jordakieva G, Crevenna R. Post-COVID: effects of physical exercise on functional status and work ability in health care personnel. Disability and Rehabilitation. 2023 Aug 28;45(18):2872-8.

- Townsend L, Dyer AH, Jones K, Dunne J, Mooney A, Gaffney F, O'Connor L, Leavy D, O'Brien K, Dowds J, Sugrue JA. Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection. PLOS One. 2020 Nov 9;15(11):e0240784.

- Van den Borst B, Peters JB, Brink M, Schoon Y, Bleeker-Rovers CP, Schers H, van Hees HW, van Helvoort H, van den Boogaard M, van der Hoeven H, Reijers MH. Comprehensive health assessment 3 months after recovery from acute coronavirus disease 2019 (COVID-19). Clinical Infectious Diseases. 2021 Sep 1;73(5):e1089-98.

- Qi R, Chen W, Liu S, Thompson PM, Zhang LJ, Xia F, Cheng F, Hong A, Surento W, Luo S, Sun ZY. Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors. MedRxiv. 2020 May 11.

- Wang X, Xu H, Jiang H, Wang L, Lu C, Wei X, Liu J, Xu S. Clinical features and outcomes of discharged coronavirus disease 2019 patients: a prospective cohort study. QJM: An International Journal of Medicine. 2020 Sep;113(9):657-65.

- Núñez-Cortés R, Rivera-Lillo G, Arias-Campoverde M, Soto-Garcia D, Garcia-Palomera R, Torres-Castro R. Use of sit-to-stand test to assess the physical capacity and exertional desaturation in patients post COVID-19. Chronic Respiratory Disease. 2021 Feb 26;18:1479973121999205.

- Jimeno‐Almazán A, Franco‐López F, Buendía‐Romero Á, Martínez‐Cava A, Sánchez‐Agar JA, Sánchez‐Alcaraz Martínez BJ, Courel‐Ibáñez J, Pallarés JG. Rehabilitation for post‐COVID‐19 condition through a supervised exercise intervention: A randomized controlled trial. Scandinavian Journal of Medicine & Science in Sports. 2022 Dec;32(12):1791-801.

- Yang G, Li Z, Li Z, Huang L, Liang P, Liu L, Li D. Meta-analysis of the impact of physical activity on the recovery of physical function in COVID-19 patients. Heliyon. 2023 Aug 22.

- Galea S, Tracy M. Participation rates in epidemiologic studies. Annals of Epidemiology. 2007 Sep 1;17(9):643-53.

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Published

2024-04-21

How to Cite

Alqahtani, H., Aljouiee, T., Alsultan, M. ., Ayyash, M., & Abu-shaheen, A. . (2024). Exercise Capacity and Fatigue in Post-COVID-19 Patients. The Journal of Medicine, Law & Public Health, 4(3), 399–402. https://doi.org/10.52609/jmlph.v4i3.125

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Original Articles